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Neuroimage. 2008 May 1;40(4):1429-35. doi: 10.1016/j.neuroimage.2008.01.003. Epub 2008 Jan 17.

Ten simple rules for reporting voxel-based morphometry studies.

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  • 1Centre for Medical Image Computing, University College London, UK.


Voxel-based morphometry [Ashburner, J. and Friston, K.J., 2000. Voxel-based morphometry-the methods. NeuroImage 11(6 Pt 1), 805-821] is a commonly used tool for studying patterns of brain change in development or disease and neuroanatomical correlates of subject characteristics. In performing a VBM study, many methodological options are available; if the study is to be easily interpretable and repeatable, the processing steps and decisions must be clearly described. Similarly, unusual methods and parameter choices should be justified in order to aid readers in judging the importance of such options or in comparing the work with other studies. This editorial suggests core principles that should be followed and information that should be included when reporting a VBM study in order to make it transparent, replicable and useful.

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