Format

Send to

Choose Destination
Gastroenterol Clin North Am. 2008 Mar;37(1):47-72, vi. doi: 10.1016/j.gtc.2007.12.006.

Syndromic colon cancer: lynch syndrome and familial adenomatous polyposis.

Author information

1
Division of Gastroenterology, Department of Medicine, William Beaumont Hospital, 3601 West Thirteen Mile Road, Royal Oak, MI 48073, USA. tusardesai@aol.com

Abstract

Colon cancer, the third leading cause of mortality from cancer in the United States, afflicts about 150,000 patients annually. More than 10% of these patients exhibit familial clustering. The most common and well characterized of these familial colon cancer syndromes is hereditary nonpolyposis colon cancer syndrome (Lynch syndrome), which accounts for about 2% to 3% of all cases of colon cancer in the United States. We review the current knowledge of familial cancer syndromes, with an emphasis on Lynch syndrome and familial adenomatous polyposis.

PMID:
18313539
DOI:
10.1016/j.gtc.2007.12.006
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center