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Semin Oncol. 2008 Feb;35(1):33-40. doi: 10.1053/j.seminoncol.2007.11.014.

Pathologic aspects of inflammatory breast cancer: part 2. Biologic insights into its aggressive phenotype.

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  • 1Department of Pathology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.


Inflammatory breast cancer (IBC) is the most aggressive and distinct form of primary breast cancer with a peculiar clinical presentation and dismal clinical outcome. This review addresses the pathologic aspects of this entity and discusses the molecular alterations involved in the highly malignant phenotype of IBC.

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