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Semin Oncol. 2008 Feb;35(1):33-40. doi: 10.1053/j.seminoncol.2007.11.014.

Pathologic aspects of inflammatory breast cancer: part 2. Biologic insights into its aggressive phenotype.

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  • 1Department of Pathology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. yungong@mdanderson.org

Abstract

Inflammatory breast cancer (IBC) is the most aggressive and distinct form of primary breast cancer with a peculiar clinical presentation and dismal clinical outcome. This review addresses the pathologic aspects of this entity and discusses the molecular alterations involved in the highly malignant phenotype of IBC.

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