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Chron Respir Dis. 2008;5(1):7-11. doi: 10.1177/1479972307082329.

Quality of life in patients with chronic obstructive pulmonary disease: the predictive validity of the BODE index.

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Department of Psychology, Joan March Hospital, Bunyola, Baleares, Spain.



Chronic obstructive pulmonary disease (COPD) is currently the fourth cause of mortality and morbility in the developed world. Patients with COPD experience a progressive deterioration of health-related quality of life (HRQOL). A new model of severity classification, the body mass index, bronchial obstruction, dyspnoea, exercise (BODE) index, has recently been proposed.


To evaluate the relationship between HRQOL and the BODE index, and the predictive ability of BODE on HRQOL measurements.


Two HRQOL questionnaires were administered, namely the Nottingham Health Profile (NHP) and St George's Respiratory Questionnaire (SGRQ), in a sample of 67 patients with severe COPD.


Pearsonś correlation coefficient analysis shows a positive correlation between the BODE index and the total scores of the specific (P < 0.001), and general HRQOL (P < 0.001); the analysis shows a significant correlation between the BODE index and the subscales of symptoms, activity and impact of SGRQ (P < 0.001) and the subscales energy and physical mobility of the NHP (P < 0.001). The regression analysis shows that the BODE index is a significant predictor of HRQOL, explaining 46,1% of the total score of the SGRQ (P < 0.001) and 14.8% of the total score of the NHP (P < 0.001).


The BODE index is good at predicting the worsening of HRQOL in patients with severe COPD.

[Indexed for MEDLINE]

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