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Curr Biol. 2008 Feb 26;18(4):R170-2. doi: 10.1016/j.cub.2007.12.023.

Checkpoint control: the journey continues.

Author information

  • 1Research Institute of Molecular Pathology , Dr. Bohr-Gasse 7, A-1030 Vienna, Austria. peters@imp.univie.ac.at

Abstract

Mad2 and p31(comet) are components of the spindle assembly checkpoint which controls the fidelity of chromosome segregation. Two recent structural studies reveal new insight into how these proteins achieve this difficult task.

PMID:
18302922
DOI:
10.1016/j.cub.2007.12.023
[PubMed - indexed for MEDLINE]
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