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Med Mycol. 2008 Feb;46(1):93-5. doi: 10.1080/13693780701642235.

Histoplasmosis as a cause for a positive Fungitell (1 --> 3)-beta-D-glucan test.

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1
MiraVista Diagnostics, 4444 Decatur Boulevard, Suite 300, Indianapolis, IN 46241, USA.

Abstract

We evaluated the Fungitell beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.

PMID:
18297546
DOI:
10.1080/13693780701642235
[Indexed for MEDLINE]

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