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Neurourol Urodyn. 2008;27(5):379-87. doi: 10.1002/nau.20554.

The minimal important change of the PRAFAB questionnaire in women with stress urinary incontinence: results from a prospective cohort study.

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1
Department of Epidemiology and Centre of Evidence Based Physiotherapy & Clinical Guidelines (CEBP), Maastricht University, Maastricht, The Netherlands. erik.hendriks@epid.unimaas.nl

Abstract

AIM:

To estimate the minimal important change (MIC) of the total PRAFAB questionnaire (PRAFAB-Q) score in women referred for physiotherapy intervention following primary or recurrent episodes of stress urinary incontinence. MIC values could be applied to individual patients and used as a threshold by which practitioners decide to continue, change or end a specific intervention.

METHODS:

Data were derived from a prospective cohort study of 279 mainly Caucasian women. MIC values were determined by: (1) the 'mean change' method, (2) the ROC method, and (3) the 95% limit cut-off point, visualized by the 'anchor-based MIC distribution'. These MIC values were compared to the smallest detectable change (SDC) accounting for measurement error. The effect of initial baseline scores on the MIC was assessed.

RESULTS:

The results of all methods used to define the MIC ranged from 1.9 to 2.7 points (SDC = 1.6) for the non-severe and 3.6-4.1 (SDC = 2.3) for the severe stratified patients. All MIC estimates were larger than the measurement error as determined by the SDC.

CONCLUSIONS:

The total PRAFAB-Q score is a brief and simple outcome measure that easily can be used to monitor progress and to interpret meaningful improvement in individual women with stress UI in everyday clinical practice.

PMID:
18288703
DOI:
10.1002/nau.20554
[Indexed for MEDLINE]
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