Iron acquisition and virulence in the motile aeromonads: siderophore-dependent and -independent systems

Experientia. 1991 May 15;47(5):416-8.

Abstract

During an infection, a microbial pathogen must acquire all of its iron from the host. Aeromonas isolated producing the siderophore amonabactin obtain iron either from host Fe-transferrin (siderophore dependent) or from host heme-containing molecules (siderophore independent). Isolates producing the siderophore enterobactin do not utilize Fe-transferrin in serum and probably rely exclusively on host heme iron.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aeromonas / metabolism
  • Aeromonas / pathogenicity*
  • Cell Movement
  • Iron / metabolism*
  • Iron Chelating Agents / metabolism*
  • Oligopeptides / metabolism
  • Siderophores
  • Virulence

Substances

  • Iron Chelating Agents
  • Oligopeptides
  • Siderophores
  • amonabactin P
  • amonabactin T
  • Iron