Format

Send to

Choose Destination
See comment in PubMed Commons below
Adv Genet. 2008;61:175-205. doi: 10.1016/S0065-2660(07)00006-5.

Global control regions and regulatory landscapes in vertebrate development and evolution.

Author information

1
Developmental Biology Unit, EMBL, 69117 Heidelberg, Germany.

Abstract

During the course of evolution, many genes that control the development of metazoan body plans were co-opted to exert novel functions, along with the emergence or modification of structures. Gene amplification and/or changes in the cis-regulatory modules responsible for the transcriptional activity of these genes have certainly contributed in a major way to evolution of gene functions. In some cases, these processes led to the formation of groups of adjacent genes that appear to be controlled by both global and shared mechanisms.

PMID:
18282506
DOI:
10.1016/S0065-2660(07)00006-5
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center