Format

Send to

Choose Destination
J Perinatol. 2008 Apr;28(4):258-63. doi: 10.1038/sj.jp.7211913. Epub 2008 Feb 14.

Maternal bisphenol-A levels at delivery: a looming problem?

Author information

1
Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109-0404, USA. vasantha@umich.edu

Abstract

OBJECTIVE:

The objective was to determine whether bisphenol-A (BPA) is found in maternal circulation of pregnant women in the US population and is related to gestational length and birth weight.

METHOD:

Circulating levels of BPA were quantified by high performance liquid chromatography-tandem mass spectrometry at delivery in 40 southeastern Michigan mothers and correlated with gestational length and birth weight of offspring.

RESULT:

Maternal levels of unconjugated BPA ranged between 0.5 and 22.3 ng ml(-1) in southeastern Michigan mothers. There was no correlation between BPA concentrations and gestational length or birth weight of offspring.

CONCLUSION:

This is the first study to document measurable levels of BPA in maternal blood of the US population. Long-term follow-up studies of offspring are needed to validate or refute concerns over human fetal exposure to synthetic exogenous steroids.

PMID:
18273031
PMCID:
PMC4033524
DOI:
10.1038/sj.jp.7211913
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center