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Eur J Pharmacol. 2008 Apr 7;583(2-3):372-8. doi: 10.1016/j.ejphar.2007.07.072. Epub 2008 Jan 19.

Mineralocorticoid receptors in brain, in health and disease: possibilities for new pharmacotherapy.

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1
University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, D-20246 Hamburg, Germany. kellner@uke.uni-hamburg.de

Abstract

Mineralocorticoid receptors in brain are involved in the regulation of stress hormone secretion and complex behavior, such as emotion, memory, and sleep. In man, the role of mineralocorticoid receptors in the pathophysiology of stress-related psychiatric disorders has still not sufficiently been characterized. Nevertheless, recent research findings promise possibilities for new pharmacotherapy via modulation of mineralocorticoid receptor function.

PMID:
18272147
DOI:
10.1016/j.ejphar.2007.07.072
[Indexed for MEDLINE]
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