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Phlebology. 2007;22(2):83-5.

Administration of 75 mg of aspirin daily for 28 days is sufficient prophylaxis against renal transplant vein thrombosis.

Author information

1
The Oxford Transplant Centre, Churchill Hospital, Headington, Oxford, UK.

Abstract

INTRODUCTION:

Early postoperative renal transplant vein thrombosis results in graft loss. We evaluate the effect of administering aspirin 75 mg daily for 28 days following transplantation.

METHODS:

Prospectively collected data on the outcome of all transplants undertaken in our unit in the five-year period from January 1997 to January 2002 were reviewed, and in cases of graft failure before three months the cause was defined.

RESULTS:

In the study period, a total of 401 transplants were undertaken (311 cadaveric and 90 living related). There was one case of renal transplant vein thrombosis (0.25%). This represents a significant reduction on the unit's historical incidence of 5.8%, P < 0.001.

CONCLUSION:

Aspirin 75 mg daily is adequate to virtually abolish renal transplant vein thrombosis and has a role in thromboprophylaxis in other situations where heparin is contraindicated.

PMID:
18268856
DOI:
10.1258/026835507780346187
[Indexed for MEDLINE]

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