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Cancer Lett. 2008 Mar 18;261(2):127-36. doi: 10.1016/j.canlet.2008.01.009. Epub 2008 Feb 11.

Non-melanoma skin cancer: importance of gender, immunosuppressive status and vitamin D.

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1
Department of Pathology, The Ohio State University, 1645 Neil Avenue, 129 Hamilton Hall, Columbus, OH 43210, USA. Oberyszyn.l@osu.edu

Abstract

Ultraviolet light B (UVB) is responsible for the majority of cutaneous damage and is believed to be the single most important etiologic agent in the development of non-melanoma skin cancers (NMSC). These skin tumors are by far the most common form of cancer in humans, with over 1 million new cases identified in the United States each year. Several risk factors exist, which increase the chance of a patient developing NMSC including gender, immunosuppressive status and more controversially vitamin D levels. The present review provides an overview of each of these areas.

PMID:
18267352
DOI:
10.1016/j.canlet.2008.01.009
[Indexed for MEDLINE]
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