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J Dtsch Dermatol Ges. 2008 Jun;6(6):480-2. doi: 10.1111/j.1610-0387.2007.06603.x.

Late onset of a facial variant of steatocystoma multiplex - calretinin as a specific marker of the follicular companion cell layer.

[Article in English, German]

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Department of Dermatology, Clinic of Dortmund gGmbH, Beurhausstrasse, Germany.


Steatocystoma multiplex is a rare,almost exclusively autosomal dominant disease of the sebaceous glands. The sites of predilection are the sternal region, upper back, axillae and proximal parts of the extremities. A 78-year-old woman developed multiple yellowish nodules only on the face over a few months. Histology revealed large cysts with a thin wall and connection to sebaceous glands. Immunohistochemical analysis showed the inner epithelial layer of the cysts was positive with calretinin.With curettage and CO2 laser therapy, a good cosmetic result was achieved.This is the first case report in the German literature of a rare sporadic form of steatocystoma multiplex with late onset and exclusive localization in the face.

[Indexed for MEDLINE]

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