Send to

Choose Destination
See comment in PubMed Commons below
Int J Clin Pract. 2008 Apr;62(4):642-8. doi: 10.1111/j.1742-1241.2008.01705.x. Epub 2008 Feb 7.

Prediabetes: a must to recognise disease state.

Author information

Department of Medicine, University of Saskatchewan, Royal University Hospital, Saskatoon, Canada.


Prediabetes mellitus (PDM) is defined as a state of abnormal glucose homeostasis in which deficiency or resistance to insulin is the hallmark. PDM precedes the development of overt type 2 DM. It is associated with increased mortality and morbidity and thus fits well with the criteria of a disease condition. Framing PDM as a disease and not a risk or a 'pre' stage for diabetes is needed to facilitate early management.


This review aims therefore to increase awareness of PDM as a disease state.


To do so, we shall preview guidelines for its diagnosis. Its prevalence and hazards will be then discussed. Finally, we shall elaborate on the current treatment guidelines.


Enough evidence support the notion that PDM is a curable disease state.


The current recommendations for the treatment of PDM should be adhered. In addition, there is a room for the use of other pharmacological agents.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center