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Clin Ter. 2007 Nov-Dec;158(6):509-13.

Computed-tomographic-guided biopsy of thoracic nodules: a revision of 583 lesions.

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1
UO di Medicina Interna, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo (FG), Italia. v.dalessandro@operapadrepio.it

Abstract

OBJECTIVES:

In pulmonary lesions, when bronchial or trans-bronchial biopsy is negative, thoracic Fine-Needle Aspiration Biopsy (FNAB) allows to obtain a cytological or histological diagnosis. The purpose of the current study is to investigate the usefulness of CT-guided FNAB to define the nature of pulmonary or thoracic lesions.

MATERIALS AND METHODS:

Between May 1995 and September 2005, 583 patients (453 males, 133 females), with thoracic lesions, without evident intrabronchial neoplasm, underwent CT-guided FNAB of thoracic nodules. FNAB was performed with 19-20-21 gauge needles, disposable soft tissue, automatic aspiration biopsy Menghini set, 10-15 cm long.

RESULTS:

In 292 patients (50%) lesions were < or = 3 cm diameter. Post biopsy pneumothorax occurred in 103 (18%) patients, with 29 patients requiring chest tube placement. Post biopsy haemoptysis occurred in 21 (4%) patients, but no patient required treatment for haemoptysis. There were 72 benign lesions (16 neoplasms) and 491 cancers (456 primary, 35 metastasis). Diagnostic accuracy was 93% and sensitivity for malignancy 93%.

CONCLUSIONS:

FNAB has excellent diagnostic rates and is a suitable technique for diagnosing thoracic lesions.

PMID:
18265716
[Indexed for MEDLINE]
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