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Am J Clin Nutr. 2007 Sep;86(3):s820-2. doi: 10.1093/ajcn/86.3.820S.

Insulin, insulin-like growth factors, insulin resistance, and neoplasia.

Author information

1
Department of Oncology, McGill University and Jewish General Hospital, Montréal, Quebec, Canada. michael.pollack@mcgill.ca

Abstract

An accumulating body of epidemiologic and laboratory evidence suggests that insulin and insulin-like growth factors influence both the risk and the prognosis of cancer. In this brief review, I highlight topics covered in my lecture on research directions in this field, including the view that metformin deserves investigation as a potential adjunct in the treatment or prevention of cancer in persons with hyperinsulinemia.

PMID:
18265475
DOI:
10.1093/ajcn/86.3.820S
[Indexed for MEDLINE]

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