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Lab Anim. 1991 Jan;25(1):46-9.

A simple non-surgical method of intrabronchial instillation for the establishment of respiratory infections in the rat.

Author information

1
SmithKline Beecham Pharmaceuticals Research Division, Betchworth, Surrey, UK.

Abstract

A technique involving intubation of weanling rats for intrabronchial instillation of infectious material has been developed to produce a respiratory infection model suitable for experimental infection studies. The technique is performed simply with the use of a metal cannula and an intravenous plastic cannula, and dispenses with the need for illumination, laryngoscopy and extensive manipulation of the animal.

PMID:
1826335
DOI:
10.1258/002367791780808130
[Indexed for MEDLINE]

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