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Asian Pac J Cancer Prev. 2007 Oct-Dec;8(4):642-4.

Primary non-gestational uterine cervical choriocarcinoma with metaplastic transformation from squamous cells.

Abstract

BACKGROUND:

Primary non-gestational uterine cervical choriocarcinoma is very unusual and although it has been hypothesized that it can arise by metaplastic transformation of cervical epithelium, solid evidence has been lacking.

CASE:

Primary non-gestational uterine cervical choriocarcinoma was diagnosed in a 47-year-old, woman undergoing tubal resection 17 years previously. A histologically- and immunohistochemically-confirmed, non-gestational cervical choriocarcinoma could be diagnosed in which there was metaplastic transformation from squamous cells . The patient underwent 5 courses of an actinomycin-D chemotherapeutic regimen and radical hysterectomy with bilateral pelvic lymphadenectomy.

CONCLUSION:

Primary non-gestational uterine cervical choriocarcinoma may indeed arise from metaplastic transformation of epithelial tissue.

PMID:
18260746
[Indexed for MEDLINE]
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