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J Nat Prod. 2008 Mar;71(3):469-72. doi: 10.1021/np8000317. Epub 2008 Feb 8.

Ciliatamides A-C, bioactive lipopeptides from the deep-sea sponge Aaptos ciliata.

Author information

1
The University of Tokyo, Tokyo, Japan. ayocha@waseda.jp

Abstract

Three lipopeptides, ciliatamides A-C ( 1- 3), were isolated from the deep-sea sponge Aaptos ciliata, and their structures were elucidated on the basis of spectroscopic and chemical methods. Ciliatamides A ( 1) and B ( 2) were found to be antileishmanial, while 2 also exhibited marginal cytotoxicity to HeLa cells.

PMID:
18257536
DOI:
10.1021/np8000317
[Indexed for MEDLINE]

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