Abstract
The marine sponge Acanthodendrilla sp. contains the proteasome inhibitor acanthosulfate ( 4), a disulfated merosesterterpene having a scalarane-type skeleton. The structure of acanthosulfate ( 4), which possesses an unusual configuration, was elucidated by interpretation of spectroscopic data.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Hydroquinones / chemistry
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Hydroquinones / isolation & purification*
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Hydroquinones / pharmacology*
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Marine Biology
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Philippines
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Porifera / chemistry*
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Proteasome Inhibitors*
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Sesterterpenes / chemistry
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Sesterterpenes / isolation & purification*
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Sesterterpenes / pharmacology*
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Stereoisomerism
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Sulfuric Acid Esters / chemistry
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Sulfuric Acid Esters / isolation & purification*
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Sulfuric Acid Esters / pharmacology*
Substances
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Hydroquinones
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Proteasome Inhibitors
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Sesterterpenes
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Sulfuric Acid Esters
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acanthosulfate
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hydroxyhydroquinone