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Cell. 2008 Jan 25;132(2):185-95. doi: 10.1016/j.cell.2008.01.003.

Evo-devo: variations on ancestral themes.

Author information

1
Howard Hughes Medical Institute and Department of Biological Chemistry, University of California, Los Angeles, CA 90095-1662, USA. ederobertis@mednet.ucla.edu

Abstract

Most animals evolved from a common ancestor, Urbilateria, which already had in place the developmental genetic networks for shaping body plans. Comparative genomics has revealed rather unexpectedly that many of the genes present in bilaterian animal ancestors were lost by individual phyla during evolution. Reconstruction of the archetypal developmental genomic tool-kit present in Urbilateria will help to elucidate the contribution of gene loss and developmental constraints to the evolution of animal body plans.

PMID:
18243095
PMCID:
PMC2280037
DOI:
10.1016/j.cell.2008.01.003
[Indexed for MEDLINE]
Free PMC Article
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