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Curr Opin Neurobiol. 2007 Dec;17(6):712-9. doi: 10.1016/j.conb.2007.11.010. Epub 2008 Jan 31.

Worm thermotaxis: a model system for analyzing thermosensation and neural plasticity.

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1
Laboratory of Molecular Neurobiology, Department of Molecular Biology, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan. m46920a@nucc.cc.nagoya-u.ac.jp

Abstract

Elucidation of the principal mechanism for sensory transduction, learning and memory is a fundamental question in neurobiology. The simple nervous system composed of only 302 neurons and the description of neural wiring combined with developed imaging techniques facilitate cellular and circuit level analysis of behavior in the nematode Caenorhabditis elegans. Recent comprehensive analysis of worm thermotaxis, an experience-modulated behavior, has begun to reveal molecular, cellular, and neural circuit basis of thermosensation and neural plasticity.

PMID:
18242074
DOI:
10.1016/j.conb.2007.11.010
[Indexed for MEDLINE]
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