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Nat Clin Pract Nephrol. 2008 Feb;4(2):80-9. doi: 10.1038/ncpneph0680.

Hereditary etiologies of hypomagnesemia.

Author information

1
Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-8837, USA. anader@parknet.pmh.org

Abstract

Magnesium ions are essential to all living cells. As the second most abundant intracellular cation, magnesium has a crucial role in fundamental metabolic processes such as DNA and protein synthesis, oxidative phosphorylation, enzyme function, ion channel regulation, and neuromuscular excitability. After presenting an overview of magnesium homeostasis, we review the etiologies of hypomagnesemia, with an emphasis on hereditary causes.

PMID:
18227801
DOI:
10.1038/ncpneph0680
[Indexed for MEDLINE]

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