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Appl Environ Microbiol. 2008 Mar;74(6):1936-40. doi: 10.1128/AEM.02509-07. Epub 2008 Jan 25.

Mucin degradation by Bifidobacterium strains isolated from the human intestinal microbiota.

Author information

1
Departamento de Microbiología y Bioquímica de Productos Lácteos, Instituto de Productos Lácteos de Asturias, CSIC, Carretera de Infiesto s/n, 33300 Villaviciosa, Asturias, Spain.

Abstract

The presence of the genes engBF (endo-alpha-N-acetylgalactosaminidase) and afcA (1,2-alpha-L-fucosidase) was detected in several intestinal Bifidobacterium isolates. Two strains of Bifidobacterium bifidum contained both genes, and they were able to degrade high-molecular weight porcine mucin in vitro. The expression of both genes was highly induced in the presence of mucin.

PMID:
18223105
PMCID:
PMC2268317
DOI:
10.1128/AEM.02509-07
[Indexed for MEDLINE]
Free PMC Article

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