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Neonatology. 2008;94(2):75-8. doi: 10.1159/000113535. Epub 2008 Jan 22.

Maternal smoking during pregnancy increases the risk of postnatal infections in preterm neonates.

Author information

1
Department of Paediatrics, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Abstract

BACKGROUND:

Maternal smoking during pregnancy is known to be associated with perinatal complications such as preterm delivery, low birth weight, and sudden infant death syndrome.

OBJECTIVE:

The purpose of this study was to evaluate the influence of smoking during pregnancy on the risk of postnatal infections in preterm neonates.

METHOD:

We examined 80 preterm infants (gestational age 24-36 weeks), of whom 40% had been exposed to tobacco smoking during pregnancy.

RESULTS:

Infections occurred in 31 infants. Gestational age and maternal smoking had a significant effect on the occurrence of infections (p < 0.001 and p = 0.015, respectively). An increase in maternal tobacco consumption by 10 cigarettes/day showed an odds ratio of 2.7 (95% confidence interval 1.1-6.4) for occurrence of infections.

CONCLUSIONS:

A significant association between maternal use of tobacco and the occurrence of infections in preterm neonates was found. Thus, campaigns about the damaging effects of tobacco are still warranted.

PMID:
18212492
DOI:
10.1159/000113535
[Indexed for MEDLINE]

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