Send to

Choose Destination
In Vivo. 2007 Nov-Dec;21(6):1027-30.

Antibacterial effect of tea-tree oil on methicillin-resistant Staphylococcus aureus biofilm formation of the tympanostomy tube: an in vitro study.

Author information

College of Natural Science, Chosun University, Gwangju, South Korea.


The antibacterial effects of tea-tree oil against the formation of methicillin-resistant Staphylococcus aureus (MRSA) biofilm on the surface of the tympanostomy tubes was evaluated.


Silicone tympanostomy tubes were pretreated with normal saline for 12 hours, the control group (n=4), with 100% tea-tree oil, experimental group A (n=3), or with 50% tea-tree oil, experimental group B (n=3). All the tubes were incubated in a MRSA solution for 2 days and then processed for evaluation using scanning electron microscopy.


The development of the biofilm mode of growth of MRSA was observed in the saline-treated control group. In contrast, only focal biofilms were present on the tube surface in experimental group A and considerable reduction of biofilm with destruction of the MRSA cells was shown in experimental group B.


From these results, the antimicrobial effect of tea-tree oil against biofilm formation on tympanostomy tubes in vitro has been verified.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center