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Arch Dermatol. 2008 Jan;144(1):67-72. doi: 10.1001/archdermatol.2007.2.

Changing trends and allergens in the patch test standard series: a mayo clinic 5-year retrospective review, january 1, 2001, through december 31, 2005.

Author information

  • 1Department of Dermatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. davis.mark2@mayo.edu

Abstract

OBJECTIVE:

To present and interpret results of patch testing with the Mayo Clinic standard series over 5 years.

DESIGN:

Retrospective study. A standardized patch testing technique was used. Data were recorded on a standardized computer program from January 1, 2001, to December 31, 2005, and analyzed.

SETTING:

Tertiary referral center.

PATIENTS:

Patients who were referred for patch testing.

INTERVENTION:

Patch testing with the "standard series," ie, a standard series of allergens used by most clinicians to identify the most common offending allergens in patients with allergic contact dermatitis.

MAIN OUTCOME MEASURES:

Number of patients patch tested, allergens used over this period, and rates of allergic patch test reactions to allergens.

RESULTS:

A total of 3854 patients (mean age, 55.1 years; age range, 6.2-99.4 years; 2576 female [66.8%]) were tested. All dermatologists in the department performed patch testing. The mean number of allergens included was 69.3 (range, 6-87). There were 2664 patients with at least 1 positive reaction (69.1%) and 1933 with 2 or more positive reactions (50.2%). Metals, fragrances, topical antibiotics, preservatives, and individual allergens used in hair-care products, topical corticosteroids, glues, plastics, and rubber were still the most common allergen groups associated with allergic patch test reactions.

CONCLUSIONS:

We describe the structure of the patch testing service at our referral center. Ongoing analysis of our patch test reaction rates allows us to recommend broad, clinically relevant, and up-to-date allergens for testing.

PMID:
18209170
DOI:
10.1001/archdermatol.2007.2
[PubMed - indexed for MEDLINE]
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