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Pediatr Allergy Immunol. 2008 Nov;19(7):587-91. doi: 10.1111/j.1399-3038.2007.00711.x. Epub 2008 Jan 16.

Content of beta-casomorphins in milk of women with a history of allergy.

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Third Department of Paediatric Diseases, Medical University, Bialystok, Poland.


The prevalence of food allergies increased over the past decade. Most symptoms of food allergy appear during the first 2 yr of life. The aim of this study was to determine the beta-casomorphin-5 and -7 (BCMs) in colostrum and milk of 12 breast-feeding women with a history and clinical manifestation of food allergy. The results were compared with the data obtained from a control group of healthy age-matched breast-feeding women. The level of BCM in women with food allergy was constant during lactation, whereas the highest level of opioid peptides was found in colostrums of healthy women with a subsequent rapid decrease in mature milk. These differences in BCMs profile between allergic and healthy breast-feeding women suggest that BCM content in the human milk may be an indicator of allergic conditions.

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