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Curr Opin Cell Biol. 2008 Feb;20(1):35-40. doi: 10.1016/j.ceb.2007.11.011. Epub 2008 Jan 18.

Navigating through models of chemotaxis.

Author information

1
Department of Electrical & Computer Engineering, Johns Hopkins University, Baltimore, MD 21218, USA. pi@jhu.edu

Abstract

Chemotaxis in eukaryotic cells involves the coordination of several related but separable processes: motility, polarization, and gradient sensing. Mathematical models that have been proposed to explain chemotaxis typically focus on only one of these processes. We summarize the strengths and weaknesses of the models and point out the need for an integrated model.

PMID:
18207721
DOI:
10.1016/j.ceb.2007.11.011
[Indexed for MEDLINE]

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