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Appl Environ Microbiol. 2008 Mar;74(5):1656-9. doi: 10.1128/AEM.02127-07. Epub 2008 Jan 18.

Prevalence and abundance of uncultivated Megasphaera-like bacteria in the human vaginal environment.

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  • 1The Research Institute for Children,1 New Orleans, Louisiana, USA.

Abstract

Cultivation-independent analysis of 16S rRNA gene sequences in vaginal samples revealed two previously unrecognized, uncultivated Megasphaera-like phylotypes. Phylogenetic analysis and environmental distribution suggest that these Megasphaera types may be unique to the vaginal environment. Quantitative PCR suggests that both phylotypes are present in higher concentrations in women with bacterial vaginosis.

PMID:
18203860
PMCID:
PMC2258643
DOI:
10.1128/AEM.02127-07
[PubMed - indexed for MEDLINE]
Free PMC Article
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