Early graft function

Clin Transpl. 1991:401-7.

Abstract

1. One-year graft survival was 83% for patients with excellent function on the first day compared with 65% for patients with poor kidney function. Patients with excellent function at 1 month had an 88% graft survival rate. 2. Patients with poor function at 1 week had lower graft survival rates than those with good function. Interestingly, those who functioned on the first day and then had poor function at 1 week had lower graft survival than those who had poor function from the first day. 3. Patients who worked full-time before transplantation had 3-5% higher 1-year graft survival compared with those who were working part-time. 4. Patients who had urine production on the first day had a 20% higher graft survival. Similar good outcomes were noted in those who did not require dialysis or have rejection episodes prior to discharge. 5. Three-month to 3-year graft survival was 30% higher for those with SCr less than 1.5 mg/dl compared to those with SCr more than 3.0 mg/dl. Patients with no rejections and no dialysis at the time of discharge had a 10% higher 3-year graft survival if Ccr was more than 90 ml/min than those with Ccr less than 60ml/min at the time of discharge. 6. Transplant patients who produced urine on the first-day posttransplant, did not require dialysis at 1 week, and had no rejection episodes by the time of discharge had the highest 1-year graft survival rates (88.7%), whereas those who had delayed function and suffered from rejection episodes had the worst graft survival (51%).(ABSTRACT TRUNCATED AT 250 WORDS)

MeSH terms

  • Creatinine / blood
  • Diuresis / physiology
  • Glomerular Filtration Rate / physiology
  • Graft Rejection / physiology
  • Graft Survival / physiology*
  • Humans
  • Kidney Function Tests*
  • Kidney Transplantation / physiology*
  • Postoperative Complications / blood*
  • Prognosis

Substances

  • Creatinine