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Small. 2008 Feb;4(2):218-24. doi: 10.1002/smll.200700283.

Iridium-complex-functionalized Fe3O4/SiO2 core/shell nanoparticles: a facile three-in-one system in magnetic resonance imaging, luminescence imaging, and photodynamic therapy.

Author information

1
Department of Chemistry, National Taiwan University, Taipei, Taiwan 106, ROC.

Abstract

Highly uniform Fe3O4/SiO2 core/shell nanoparticles functionalized by phosphorescent iridium complexes (Ir) have been strategically designed and synthesized. The Fe3O4/SiO2(Ir) nanocomposite demonstrates its versatility in various applications: the magnetic core provides the capability for magnetic resonance imaging and the great enhancement of the spin-orbit coupling in the iridium complex makes it well suited for phosphorescent labeling and simultaneous singlet oxygen generation to induce apoptosis.

PMID:
18196505
DOI:
10.1002/smll.200700283
[Indexed for MEDLINE]

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