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An Pediatr (Barc). 2008 Jan;68(1):9-12.

[Incontinentia pigmenti. Initial and long-term characteristics].

[Article in Spanish]

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Servicios de Infecciosas, Hospital Materno-Infantil La Paz, Madrid, España.


We report two cases of incontinentia pigmenti diagnosed in the neonatal period. Both patients presented with disseminated vesicular lesions. Neither patient had extra-dermatological symptoms at diagnosis. The definitive diagnosis was established by cutaneous biopsy. In the initial phase of the disease, the lesions can be similar to those of herpes simplex infection, but characteristic distribution and clinical course allow the differential diagnosis to be established. This disease should be included in the differential diagnosis of vesicular rashes because early detection allows better management of the possible associated systemic manifestations.

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