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J Affect Disord. 2008 Aug;109(3):300-4. doi: 10.1016/j.jad.2007.12.002. Epub 2008 Jan 11.

The relationship between mental disorders, quality of life, and pregnancy: findings from a nationally representative sample.

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  • 1Department of Psychiatry, University of Manitoba, Winnipeg, Canada.



The present study examined health-related quality of life (HRQOL) and the prevalence of mental disorders in pregnant and past-year pregnant women compared to non-pregnant women.


Data came from the National Epidemiologic Survey on Alcohol and Related Conditions. Three groups of women (ages 18-44) were compared: currently pregnant (n=451), past-year pregnant (n=1061), and not pregnant (n=10,544). Past-year mood, anxiety and substance use disorders were assessed by the Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-IV version. HRQOL was measured by the Medical Outcomes Study Short Form (SF-12). All analyses included sociodemographics as covariates.


Multiple logistic regression analyses showed that pregnant women were less likely than non-pregnant women to have depression and alcohol abuse or dependence; and less likely than past-year pregnant women to have depression and mania. Past-year pregnant women were less likely than non-pregnant women to have social phobia and alcohol dependence or abuse. Multiple linear regression analyses demonstrated that pregnant and non-pregnant women had higher mental component scores than past-year pregnant women. Physical component scores were lower in pregnant women than in non-pregnant and past-year pregnant groups.


This was a cross-sectional survey and the causality of relationships cannot be inferred.


Results suggest that pregnant women have a lower likelihood of mental disorder than both non-pregnant and past-year pregnant women.

[PubMed - indexed for MEDLINE]
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