Format

Send to

Choose Destination
Drug Discov Today. 2008 Jan;13(1-2):1-13. doi: 10.1016/j.drudis.2007.10.003. Epub 2007 Nov 26.

Microfluidics for drug discovery and development: from target selection to product lifecycle management.

Author information

1
Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

Microfluidic technologies' ability to miniaturize assays and increase experimental throughput have generated significant interest in the drug discovery and development domain. These characteristics make microfluidic systems a potentially valuable tool for many drug discovery and development applications. Here, we review the recent advances of microfluidic devices for drug discovery and development and highlight their applications in different stages of the process, including target selection, lead identification, preclinical tests, clinical trials, chemical synthesis, formulations studies and product management.

PMID:
18190858
PMCID:
PMC2700821
DOI:
10.1016/j.drudis.2007.10.003
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center