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Biochem Biophys Res Commun. 2008 Mar 21;367(4):888-92. doi: 10.1016/j.bbrc.2008.01.003. Epub 2008 Jan 9.

Grimelysin, a novel metalloprotease from Serratia grimesii, is similar to ECP32.

Author information

1
Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.

Abstract

Limited actin proteolysis is the hallmark of bacterial metalloprotease ECP32. While ECP32 has long been considered an Escherichia coli protein, the N-terminal amino acid sequence of the active enzyme described previously, could not been retrieved in the E. coli genome. We cloned, sequenced and characterized Serratia grimesii protease grimelysin and show that grimelysin is similar to the previously described protease ECP32.

PMID:
18190782
DOI:
10.1016/j.bbrc.2008.01.003
[Indexed for MEDLINE]

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