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Cogn Affect Behav Neurosci. 2007 Dec;7(4):413-22.

Probing human and monkey anterior cingulate cortex in variable environments.

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  • 1University of Oxford, Oxford, England.

Abstract

Previous research has identified the anterior cingulate cortex (ACC) as an important node in the neural network underlying decision making in primates. Decision making can, however, be studied under a large variety of circumstances, ranging from the standard well-controlled lab situation to more natural, stochastic settings, in which multiple agents interact. Here, we illustrate how these different varieties of decision making studied can influence theories ofACC function in monkeys. Converging evidence from unit recordings and lesion studies now suggest that the ACC is important for interpreting outcome information according to the current task context to guide future action selection. We then apply this framework to the study of human ACC function and discuss its potential implications.

PMID:
18189014
PMCID:
PMC2519031
[PubMed - indexed for MEDLINE]
Free PMC Article
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