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Contact Dermatitis. 2008 Feb;58(2):67-75. doi: 10.1111/j.1600-0536.2007.01267.x.

Immunological occupational contact urticaria and contact dermatitis from proteins: a review.

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  • 1Department of Dermatology, Hospital de Curry Cabral, Rua da BeneficĂȘncia, no 8, 1069-166 Lisbon, Portugal.


Protein contact with the skin can be associated with 2 major clinical conditions: contact urticaria and protein contact dermatitis. This article reviews the pathogenesis, clinical pictures and the literature on the proteins having caused immunological occupation-related skin problems, i.e. fruits, vegetables, spices, plants, and woods; animal proteins; grains and enzymes, all affecting a wide variety of jobs. This is illustrated with some cases observed in the contact-allergy unit in Leuven.

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