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Clin Infect Dis. 2008 Feb 1;46 Suppl 2:S115-8; discussion S144-51. doi: 10.1086/523329.

Regulation of probiotic substances as ingredients in foods: premarket approval or "generally recognized as safe" notification.

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1
Division of Biotechnology and GRAS Notice Review, Office of Food Additive Safety, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, Maryland 20740, USA. antonia.mattia@fda.hhs.gov

Abstract

This article discusses options and examples of regulations or "generally recognized as safe" determinations that are related to microorganisms in food. A balanced picture of information about the microorganism and its characteristics is needed to make conclusions about its safety.

PMID:
18181714
DOI:
10.1086/523329
[Indexed for MEDLINE]
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