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Pediatr Infect Dis J. 2008 Feb;27(2):178-80. doi: 10.1097/INF.0b013e31815bb6c5.

Random colony selection versus colony morphology for detection of multiple pneumococcal serotypes in nasopharyngeal swabs.

Author information

1
Menzies School of Health Research, Darwin, Northern Territory, Australia.

Abstract

Detection of multiple serotype carriage is important in understanding pneumococcal epidemiology. We compared random selection of 4 pneumococcal colonies per swab with selection by colony morphology. Multiple serotypes were detected in 20% of 98 swabs; 14% by morphology and 17% by random selection. Selection by morphology was more efficient per colony, but underestimated the true rate of multiple carriage.

PMID:
18174871
DOI:
10.1097/INF.0b013e31815bb6c5
[Indexed for MEDLINE]

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