Format

Send to

Choose Destination
J Am Chem Soc. 2008 Jan 23;130(3):833-5. doi: 10.1021/ja077406x. Epub 2008 Jan 1.

Copper-catalyzed aerobic oxidative amidation of terminal alkynes: efficient synthesis of ynamides.

Author information

1
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA.

Abstract

A copper-catalyzed method for the preparation of ynamides has been identified that proceeds via aerobic oxidative coupling of terminal alkynes with various nitrogen nucleophiles, including cyclic carbamates, amides and ureas, and N-alkyl-arylsulfonamides and indoles.

PMID:
18166058
DOI:
10.1021/ja077406x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center