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Pediatr Infect Dis J. 2008 Jan;27(1):77-9.

Liposomal amphotericin B associated with severe hyperphosphatemia.

Author information

1
Division of Pediatric Nephrology, Department of Pediatrics, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, USA. suthersm@stanford.edu

Abstract

We report 4 patients who developed hyperphosphatemia while receiving liposomal amphotericin B to treat an invasive fungal infection. Resolution of the hyperphosphatemia occurred after transition to amphotericin B lipid complex. This phenomenon may occur more commonly in patients with mild to moderate renal insufficiency.

PMID:
18162947
DOI:
10.1097/INF.0b013e31815922a3
[Indexed for MEDLINE]

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