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Contact Dermatitis. 2008 Jan;58(1):24-7.

A study of the sensitization rate to cocamidopropyl betaine in patients patch tested in a university hospital of Beijing.

Author information

1
Department of Dermatology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing 100083, China. zoonli@sina.com

Abstract

BACKGROUND:

The prevalence of sensitization to cocamidopropyl betaine (CAPB) in China has not been reported.

OBJECTIVE:

This study is to evaluate the prevalence of CAPB sensitization in patients patch tested in Peking University Third Hospital, Beijing.

METHODS:

429 consecutive patients with suspected allergic contact dermatitis were patch tested with CAPB 1.0% aqueous, 3-dimethylaminopropylamine (DMAPA) 1.0% aqueous as well as a modified European standard series of allergens from June 2005 to August 2006.

RESULTS:

42 patients (9.8%) had a positive reaction to CAPB. 25 of them (59.5%) were considered relevant. Of those, 7 were head and/or neck dermatitis, 4 hand dermatitis, 1 cheilitis, and the other 13 patients were widespread dermatitis. 10 out of 429 (2.3%) patients reacted to DMAPA. Of those, 8 were relevant and 6 of them also reacted to CAPB.

CONCLUSION:

The rate of CAPB sensitization in our study is higher than previously reported elsewhere. CAPB is a common cosmetic allergen in Beijing. Both CAPB and DMAPA should be tested in patients with suspected cosmetic dermatitis.

[Indexed for MEDLINE]

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