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Brain Res. 1991 Dec 24;568(1-2):330-4.

Fibronectin immunoreactivity in neural trauma.

Author information

1
Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis 95616-8643.

Abstract

The presence of extracellular matrix protein fibronectin (FN) at the site of neural trauma was examined using immunohistochemical methods. At 2, 4 and 7 days following a penetrating wound through the rat cerebral cortex, FN staining was detected in the neuropil and in non-neuronal cells adjacent to the wound. FN-stained cells were GFAP-negative and were identified as brain macrophages based on cell surface staining for CR3 complement receptor. Our findings suggest a role for FN in the repair of neural trauma.

PMID:
1814578
DOI:
10.1016/0006-8993(91)91421-v
[Indexed for MEDLINE]

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