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Dev Pharmacol Ther. 1991;17(1-2):116-20.

Chloral hydrate toxicity in a term infant.

Author information

1
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas.

Abstract

Chlorate hydrate is commonly used for neonatal sedation, but blood levels are infrequently monitored, reflecting an underemphasis of acute toxic effects. This report describes a case of chloral hydrate toxicity in a term infant with cardiac, renal, neurologic, bladder and gastrointestinal dysfunction. The effects of exchange transfusion are described as well as pharmacokinetics.

PMID:
1811917
DOI:
10.1159/000457507
[Indexed for MEDLINE]

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