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Nano Lett. 2008 Jan;8(1):310-6. Epub 2007 Dec 21.

Single particle X-ray diffractive imaging.

Author information

1
Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, California 94550, USA. bogan2@llnl.gov

Abstract

In nanotechnology, strategies for the creation and manipulation of nanoparticles in the gas phase are critically important for surface modification and substrate-free characterization. Recent coherent diffractive imaging with intense femtosecond X-ray pulses has verified the capability of single-shot imaging of nanoscale objects at suboptical resolutions beyond the radiation-induced damage threshold. By intercepting electrospray-generated particles with a single 15 femtosecond soft-X-ray pulse, we demonstrate diffractive imaging of a nanoscale specimen in free flight for the first time, an important step toward imaging uncrystallized biomolecules.

PMID:
18095739
DOI:
10.1021/nl072728k

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