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Am J Transplant. 2008 Jan;8(1):250-2. Epub 2007 Dec 18.

Does the permanent portacaval shunt for a small-for-size graft in a living donor liver transplantation do more harm than good?

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Department of General Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.


In order to obviate a small-for-size graft syndrome (SFSGS), a portacaval (PC) shunt had been considered in a case of adult-to-adult living donor liver transplantation (AA-LDLT). In a recent AA-LDLT case, we adopted the PC shunt to resolve SFSGS; however, graft atrophy was observed in the late period of LDLT, thereby resulting in liver dysfunction. Due to the surgical closure of the PC shunt at 11 months post-LDLT, the graft regenerated gradually and resulted in the recovery of the liver function. This experience indicates that the portacaval shunt would overcome SFSGS in the early period of LDLT, while it would cause the graft atrophy and the graft dysfunction in the late period of LDLT.

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