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Arch Dermatol. 2007 Dec;143(12):1543-6.

Smoking and skin aging in identical twins.

Author information

1
Department of Dermatology, Case Western Reserve University, Bolwell Health Center, 11100 Euclid Ave, Ste 3100, Cleveland, OH 44106, USA. doshid@gwu.edu

Abstract

BACKGROUND:

A twin pair can provide a rare opportunity to control for genetic susceptibility and exposure variables, which often serve as major confounders in population-based studies on the relationship between smoking and skin aging.

OBSERVATIONS:

We describe a unique twin pair who spent not only their first 2 decades of life together but also in their later decades had the same type of job at the same latitude, resulting in well-matched levels of significant sun exposure. However, the twins differed markedly in regard to smoking history; the twin with an approximately 52.5-pack-year smoking history showed more severe skin aging than did the nonsmoking twin.

CONCLUSION:

The difference in skin aging illustrated by this twin pair may serve as a motivator for smoking cessation.

PMID:
18087005
DOI:
10.1001/archderm.143.12.1543
[Indexed for MEDLINE]

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