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Cell. 2007 Dec 14;131(6):1044-6.

A seminal finding for understanding HIV transmission.

Author information

1
Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA. nroan@gladstone.ucsf.edu

Abstract

Although the worldwide incidence of HIV infection is high, the retrovirus displays a surprisingly low infectivity in vitro. As a potential explanation for this discrepancy, M√ľnch et al. (2007) now identify and characterize a factor found in human semen that under certain conditions can enhance HIV infectivity by more than 100,000-fold.

PMID:
18083095
DOI:
10.1016/j.cell.2007.11.030
[Indexed for MEDLINE]
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